MergeReference: A Tool for Merging Reference Panels for HLA Imputation
Genomics & Informatics
;
: 108-111, 2017.
Article
in English
| WPRIM
| ID: wpr-127727
ABSTRACT
Recently developed computational methods allow the imputation of human leukocyte antigen (HLA) genes using intergenic single nucleotide polymorphism markers. To improve the imputation accuracy in HLA imputation, it is essential to increase the sample size and the diversity of alleles in the reference panel. Our software, MergeReference, helps achieve this goal by providing a streamlined pipeline for combining multiple reference panels into one.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sample Size
/
Polymorphism, Single Nucleotide
/
Alleles
/
HLA Antigens
/
Leukocytes
/
Major Histocompatibility Complex
Limits:
Humans
Language:
English
Journal:
Genomics & Informatics
Year:
2017
Type:
Article
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