Genetic Diversity among Virulent Mega Plasmids pXO1 and pXO2 of Bacillus anthracis Isolated in Korea
Journal of Bacteriology and Virology
;
: 253-264, 2003.
Article
in Korean
| WPRIM
| ID: wpr-128198
ABSTRACT
We compared genetic variations in virulence mega plasmids pXO1 and pXO2 of twenty-seven Bacillus anthracis strains from Korean patients and environmental samples together with those of Bacillus anthracis Sterne, Pasteur and A2012 standard strains. Genetic variations were analyzed in twenty-three variable regions (ten and thirteen variablenumber tandem repeats and insertion/deletions in pXO1 and pXO2, respectively). The pXO1 plasmids were classified into 7 groups and pXO2 plasmids to 12 groups. Discrete phylogenic lineages could be differentiated between environmental and clinical strains by UPGMA (unweighted pair group method with average) method. In addition, clinical strains showed more variations than environmental isolates. The pXO2 plasmid appeared genetically more unstable than pXO1. A general plasmid genotype could be suggested for Korean soil isolates since they mostly clustered into a representative group.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasmids
/
Soil
/
Bacillus
/
Bacillus anthracis
/
Genetic Variation
/
Virulence
/
Tandem Repeat Sequences
/
Genotype
/
Korea
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of Bacteriology and Virology
Year:
2003
Type:
Article
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