Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report
Clinical and Molecular Hepatology
;
: 180-182, 2015.
Article
in English
| WPRIM
| ID: wpr-128613
ABSTRACT
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs. However, a 33-year-old male patient who was admitted with Stevens-Johnson syndrome after taking lamotrigine for 15 days experienced hepatic failure and died 5 days after admission. This case demonstrates the importance of realizing that lamotrigine can lead to fatal hepatic failure, and that tests for the normal liver function should be performed when administering lamotrigine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aspartate Aminotransferases
/
Triazines
/
Stevens-Johnson Syndrome
/
Liver Failure
/
Alanine Transaminase
/
Drug Hypersensitivity
/
Liver
/
Anticonvulsants
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Clinical and Molecular Hepatology
Year:
2015
Type:
Article
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