A Case of Coumarin-Induced Skin Necrosis / 대한피부과학회지
Korean Journal of Dermatology
;
: 1133-1135, 2000.
Article
in Korean
| WPRIM
| ID: wpr-12877
ABSTRACT
Coumarin-induced skin necrosis is a rare complication of oral administration of coumarin derivatives. Clinically, the lesions begin with well-defined purpuric patches and progress to bullae and necrosis on the trunk, buttock or female breast. Histopathologic findings show a fibrinoid degeneration or thrombus formation in the dermal blood vessels with occasional vessel rupture and hemorrhage. We report a 77-year-old man who suffered from a typical necrotic patch on his right buttock developing during the course of coumarin therapy. Our case was diagnosed as coumarin-induced skin necrosis, based on the characteristic clinical course and histopathologic findings.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rupture
/
Skin
/
Thrombosis
/
Blood Vessels
/
Breast
/
Buttocks
/
Administration, Oral
/
Hemorrhage
/
Necrosis
Limits:
Aged
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2000
Type:
Article
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