A Case of Sweet's Syndrome Associated with Myelodysplastic Syndrome / 대한피부과학회지

ABSTRACT

We report a case of Sweet's syndrome associated with myelodysplastic syndrome in a 48-year-old male patient who presented with high fever, general weakness and tender, erythematous, painful vesiculopapules and plaques with crust on the face, extremities and perianal area. Skin biopsy revealed dense infiltration of neutrophilis in the upper and mid-dermis. Peripheral blood smear showed normocytic normochromic anemic feature with thrombocytopenia. Bone marrow biopsy revealed dyspoiesis of marrow cells, consistent with myelodysplastic syndrome. He was treated with methylprednisolone 50mg/day and general symptoms improved immediately with drop of fever and skin lesions began to improve within 2 days.