Application of the QuantiFERON(R)-TB Gold Test in Two Cases of Erythema Induratum of Bazin / 대한피부과학회지
Korean Journal of Dermatology
;
: 850-854, 2009.
Article
in Korean
| WPRIM
| ID: wpr-129152
ABSTRACT
Erythema induratum of Bazin is a chronic, nodular subcutaneous eruption usually occurring on the lower legs of young women. Erythema induratum of Bazin hasbeen regarded as a tuberculide, a hypersensitivity response to Mycobacterium tuberculosis. The pathogenesis of erythema induratum of Bazin associated with tuberculosis is still debatable because mycobacteria cannot be cultured from the skin lesions. QuantiFERON(R)-TB Gold test detects INF-gamma released by T cells in response to Mycobacterium tuberculosis-specific antigens, which offers an improved diagnostic test of latent tuberculosis infection. We experienced two cases of erythema induratum of Bazin, which showed normal chest X-ray and negative TB-PCR. However the QuantiFERON(R)-TB Gold test was positive which led us to a diagnosis of latent tuberculosis infection. Both patients were treated with anti-tuberculosis medications, which was followed by successful resolution of the skin lesions. Therefore, we report the application of the QuantiFERON(R)-TB Gold test for the confirmation of latent tuberculosis infection in erythema induratum of Bazin patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Thorax
/
Tuberculosis
/
Tuberculosis, Cutaneous
/
T-Lymphocytes
/
Erythema Induratum
/
Interferon-gamma
/
Diagnostic Tests, Routine
/
Erythema
/
Latent Tuberculosis
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2009
Type:
Article
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