Radiation effect on the stages of amelogenesis in the rat incisor / 대한구강악안면방사선학회지

ABSTRACT

The purpose of this study was to investigate the radiation effect on the stages of amelogenesis. Twenty 11-day-old rats which were irradiated by 4GY of gamma radiation on the 19th prenatal day were used for the experimental group and twenty 11-day-old rats which were not irradiated were used for the control group. The length of each zone of amelogenesi s were measured on the sagittal section using a light microscopic enlargement at 400 X the normal view while the morphol ogic changes of ameloblasts of each zone were observed electron-microscopically. The obtined results were as followed 1. The length of the region of facing pulp and facing dentin of the zone of presecretion were increased by 11.5%(P0.05). 4. Electron-microscopically, enlargement of the cell membrane, rER, mitochondria, and nuclear membrane were observed. These changes were mostly severe in the zone of maturation.