Comparison of Factors Which Influence the Brachial-Ankle Pulse Wave Velocity in Pre- and Postmenopausal Women / 대한폐경학회지
The Journal of Korean Society of Menopause
;
: 86-92, 2010.
Article
in Korean
| WPRIM
| ID: wpr-129379
ABSTRACT
OBJECTIVES:
The aim of this study was to compare the factors which influence the brachial-ankle pulse wave velocity (baPWV) in pre- and post-menopausal women. We also investigated the association of menopause with arterial stiffness measured by baPWV.METHODS:
We performed a retrospective review of 241 postmenopausal women who attended the health promotion center for a routine checkup. Simple and multiple regression analyses were performed to determine the parameters influencing baPWV in pre- and postmenopausal women. Multiple logistic regression analysis was performed to identify the independent parameters related to increased of arterial stiffness.RESULTS:
Multiple regression analysis showed that diastolic blood pressure (DBP; beta = 0.402, P = 0.009) was identified as an independent determinant for baPWV in premenopausal women, and DBP (beta = 0.329, P = 0.021) and the neutrophil-to-lymphocyte ratio (NLR; beta = 0.210, P = 0.016) were identified as independent determinants for baPWV in postmenopausal women. The odds ratio (95% CI) of menopause for a high baPWV was 2.666 (1.025~6.937).CONCLUSION:
The NLR is associated with arterial stiffness in postmenopausal women. Consequently, inflammation is thought to play a crucial role in increased arterial stiffness in postmenopausal women. Menopause is associated with a high baPWV, suggesting that changes in the concentrations of sex hormones during the menopausal transition may influence arterial stiffness in clinically healthy women.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Gonadal Steroid Hormones
/
Blood Pressure
/
Menopause
/
Logistic Models
/
Odds Ratio
/
Retrospective Studies
/
Vascular Stiffness
/
Pulse Wave Analysis
/
Health Promotion
/
Inflammation
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
Korean
Journal:
The Journal of Korean Society of Menopause
Year:
2010
Type:
Article
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