Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome
Obstetrics & Gynecology Science
;
: 397-402, 2016.
Article
in English
| WPRIM
| ID: wpr-129954
ABSTRACT
Pregnant women with antiphospholipid syndrome (APS) carry a high risk of arterial or venous thrombosis. Such thrombotic conditions occur more frequently in patients with triple positivity to antiphospholipid antibodies or with high antibody titers. Hepatic infarction is a rare complication in pregnant women with APS, and it sometimes mimics HELLP syndrome. This report describes a preeclamptic pregnant woman with APS who had high titers of three antiphospholipid antibodies. She experienced severe epigastric pain with elevated liver enzymes; in addition, she had tachycardia and tachypnea. The clinical findings suggested hepatic infarction and pulmonary thromboembolism, a partial manifestation of catastrophic APS. Therefore, she underwent emergent cesarean section at 25+2 weeks of gestation. After the delivery, her laboratory test indicated HELLP-like features, and computed tomography confirmed hepatic infarction and pulmonary micro-thromboembolism. Here, we report a case of a partial manifestation of catastrophic APS in a pregnant woman with triple antibody positivity, including a brief literature review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pulmonary Embolism
/
Tachycardia
/
Cesarean Section
/
Antiphospholipid Syndrome
/
HELLP Syndrome
/
Antibodies, Antiphospholipid
/
Venous Thrombosis
/
Pregnant Women
/
Tachypnea
/
Infarction
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2016
Type:
Article
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