Langerhans Cell Histiocytosis Presenting as a Solitary Nodule / 대한피부과학회지
Korean Journal of Dermatology
;
: 459-462, 2001.
Article
in Korean
| WPRIM
| ID: wpr-129979
ABSTRACT
Langerhans cell histiocytosis, previously called histocytosis X, is a disease of unknown cause characterized by the proliferation of a distinct cell type that is S-100 and CD1a positive and contains cytoplasmic langerhans granules. We report a case of langerhans cell histiocytosis, which a 10-year-old girl presented as a solitary nodule without systemic involvement. Histologic examination of the nodule showed a dense dermal infiltrate of histiocytic cells with bean-shaped nuclei. These cells reacted with antibodies to S-100 and CD1a. Ultrastructural analysis showed Birbeck granules in the cytoplasm of the histiocytic cells. We confirmed langerhans cell histicytosis presenting as a solitary nodule by above findings.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Histiocytosis, Langerhans-Cell
/
Cytoplasm
/
Antibodies
Limits:
Child
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2001
Type:
Article
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