Interstitial Lung Disease Associated with Combination Chemotherapy of Oxaliplatin, 5-Fluorouracil, and Leucovorin

Sul PARK; Jae-Jin JUNG; Goeng-Bae KIM; Hyung-Sik YOON; Sang-Hun KO; Jae-Ee KO; Yeun-Seun LEE

Interstitial Lung Disease Associated with Combination Chemotherapy of Oxaliplatin, 5-Fluorouracil, and Leucovorin / 대한소화기학회지

Sul PARK; Jae-Jin JUNG; Goeng-Bae KIM; Hyung-Sik YOON; Sang-Hun KO; Jae-Ee KO; Yeun-Seun LEE.

The Korean Journal of Gastroenterology ; : 340-343, 2010.

Article in Korean | WPRIM | ID: wpr-130416

ABSTRACT

ABSTRACT

Oxaliplatin with 5-fluorouracil plus leucovorin (FOLFOX) has become the standard treatment in patients with colorectal cancer. Among known toxicities induced by oxaliplatin, hematological, gastrointestinal and neurological toxicities are common. However, acute pulmonary toxicity associated with oxaliplatin is unusual. One case of interstitial lung disease associated with the FOLFOX protocol is reported here.

Subject(s)

Aged; Humans; Male; Antineoplastic Agents/adverse effects; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms/drug therapy; Fluorouracil/adverse effects; Leucovorin/adverse effects; Lung Diseases, Interstitial/chemically induced; Organoplatinum Compounds/adverse effects

Oxaliplatin; Colon cancer; Interstitial lung diseases

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Organoplatinum Compounds / Colorectal Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Leucovorin / Lung Diseases, Interstitial / Fluorouracil / Antineoplastic Agents Type of study: Practice guideline Limits: Aged / Humans / Male Language: Korean Journal: The Korean Journal of Gastroenterology Year: 2010 Type: Article

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