Pulsatile GnRH therapy in male patients with hypogonadotropic hypogonadism / 대한비뇨기과학회지
Korean Journal of Urology
;
: 637-641, 1991.
Article
in Korean
| WPRIM
| ID: wpr-130498
ABSTRACT
The effects of pulsatile GnRH therapy have been studied for the treatment of different forms of hypogonadotropic hypogonadism, including idiopathic hypogonadotropic hypogonadism and hypogonadism developed as a result of treatment with combination of surgery and irradiation for pituitary or hypothalamic tumor. GnRH was administered subcutaneously in a dose of 10ug every 2 hours with the pulsatile infusion pump. With GnRH therapy, all patients improved secretion of LH, FSH and testosterone. Testicular volumes increased. Spermatogenesis was induced in 4 patients. Pulsatile GnRH therapy is an effective treatment for idiopathic hypogonadotropic hypogonadism and can have a role in hypogonadism previously treated with combination of surgery and irradiation for pituitary or hypothalamic tumor.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spermatogenesis
/
Testosterone
/
Infusion Pumps
/
Gonadotropin-Releasing Hormone
/
Hypogonadism
/
Hypothalamic Neoplasms
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Urology
Year:
1991
Type:
Article
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