Generalized Dowling-Degos Disease: Case Reports
Annals of Dermatology
;
: 360-364, 2013.
Article
in English
| WPRIM
| ID: wpr-131861
ABSTRACT
Dowling-Degos disease (DDD) is a rare autosomal dominant trait characterized by numerous, symmetrical, progressive and pigmented macules over the axillae, groins, face, neck, arms and trunk as well as scattered comedo-like lesions (dark dot, follicles) and pitted acneiform scars. Histopathology is diagnostic testing using a distinctive form of acanthosis, characterized by an irregular elongation of thin branching rete ridges, with a concentration of melanin at the tips. We report cases of generalized DDD in a single family with autosomal dominant penetrance. DDD can be presented in a generalized form with hypopigmented lesions instead of reticulate hyperpigmentation confined to the flexor areas. This form can be differentiated from DUH by histopathology.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arm
/
Skin Diseases, Genetic
/
Axilla
/
Cicatrix
/
Skin Diseases, Papulosquamous
/
Hyperpigmentation
/
Penetrance
/
Dichlorodiphenyldichloroethane
/
Diagnostic Tests, Routine
/
Groin
Limits:
Humans
Language:
English
Journal:
Annals of Dermatology
Year:
2013
Type:
Article
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