Association Study of the Relationship between Endometriosis and Polymorphism of p53 Codon 72 / 대한불임학회지
Korean Journal of Fertility and Sterility
;
: 311-316, 2002.
Article
in Korean
| WPRIM
| ID: wpr-131935
ABSTRACT
OBJECTIVE:
The present study was performed to evaluate the association of p53 codon 72 polymorphism and endometriosis. MATERIALS ANDMETHODS:
We investigate 74 women who were operated for endometriosis and 93 women who had no endometriotic lesion proved by operation. Polymerase chain reaction was used to detect p53 codon polymorphisms.Result:
We have found no significant difference between endometriosis and control group in the p53 codon polymorphism. The respective proportion of arginine homozygotes, heterozygotes and proline homozygotes in endometriosis group were 18.9%, 62.2% and 18.9%, respectively, and were 12.9%, 75.2% and 11.9%, respective in the group without endometriosis.CONCLUSION:
Endometriosis is not associated with p53 polymorphism in Korean endometriosis patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arginine
/
Codon
/
Proline
/
Polymerase Chain Reaction
/
Endometriosis
/
Heterozygote
/
Homozygote
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Fertility and Sterility
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS