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Successful Pamidronate Treatment of Osteogenesis Imperfecta Type III Infant with Multiple Fractures
Annals of Pediatric Endocrinology & Metabolism ; : 194-197, 2012.
Article in English | WPRIM | ID: wpr-132351
ABSTRACT
Osteogenesis imperfect (OI) is a generalized connective tissue disorder. We report the female neonate case with OI type III who showed severe bone deformities and fractures in utero. At birth, she showed multiple fractures in the clavicle, rib, femur, and wormian bone in the skull X-ray. We initiated pamidronate disodium infusion 30 mg/m2 in cycles of 3 consecutive days from when she was 4 days old, monthly for the first 3 months and every 2 months thereafter without adverse effects.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteogenesis / Osteogenesis Imperfecta / Ribs / Skull / Congenital Abnormalities / Bone Density / Clavicle / Connective Tissue / Parturition / Diphosphonates Limits: Female / Humans / Infant / Infant, Newborn Language: English Journal: Annals of Pediatric Endocrinology & Metabolism Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteogenesis / Osteogenesis Imperfecta / Ribs / Skull / Congenital Abnormalities / Bone Density / Clavicle / Connective Tissue / Parturition / Diphosphonates Limits: Female / Humans / Infant / Infant, Newborn Language: English Journal: Annals of Pediatric Endocrinology & Metabolism Year: 2012 Type: Article