Multiple Skin Colored Nodules on both Legs in Patient with Positive QuantiFERON®-TB Gold Test
Annals of Dermatology
;
: 95-99, 2017.
Article
in English
| WPRIM
| ID: wpr-132697
ABSTRACT
Nodular tuberculid (NT) was originally described by Jordaan et al. in 2000 in 4 patients from South Africa. It appeared as nodules on the legs; the pathologic changes were situated in the deep dermis and adjacent subcutaneous fat. A 34-year-old woman visited our hospital with subcutaneous skin-colored or slightly erythematous round to oval nodules. Skin biopsies revealed granulomatous inflammation at the dermo-subcutaneous junction with vasculitis. Chest X-ray, tuberculosus (TB)-polymerase chain reaction and TB culture of the skin specimen were normal. A QuantiFERON®-TB Gold test (QUIAGEN, Germany) was positive, which suggested a diagnosis of latent TB infection. The patient was treated with anti-TB medication and her condition has not recurred. Herein, we report a case of a patient with latent TB diagnosed by a positive QuantiFERON®-TB Gold test whose skin lesions had the clinical and histopathologic features of NT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
South Africa
/
Thorax
/
Tuberculosis, Cutaneous
/
Vasculitis
/
Biopsy
/
Skin Pigmentation
/
Dermis
/
Diagnosis
/
Subcutaneous Fat
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
Africa
Language:
English
Journal:
Annals of Dermatology
Year:
2017
Type:
Article
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