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Central Retinal Artery Obstruction in Protein S Deficiency
Journal of the Korean Ophthalmological Society ; : 2017-2020, 2008.
Article in Korean | WPRIM | ID: wpr-132886
ABSTRACT

PURPOSE:

To report a case of central retinal artery obstruction (CRAO) caused by protein S deficiency. CASE

SUMMARY:

A 36-year-old man presented with acutely reduced visual acuity in the right eye. The patient had no other diseases such as diabetes mellitus or hypertension. The visual acuity was 20/20 in the right eye and light perception in the left eye. Afferent pupillary defect was observed in theleft eye. Fundus examination showed diffuse retinal opacification and a cherry-red spot at the macula. Thus the patient was diagnosed with CRAO in the left eye. There were no abnormal findings on routine hematologic tests including blood coagulation test. Protein C activity, antithrombin III activation, anticardiolipin antibody were within normal limits but protein S activity was decreased. Thus, the patient was diagnosed with CRAO with protein S deficiency.

CONCLUSIONS:

Coagulation factors such as protein S need to be measuredin cases of CRAO in young patients without medical problems.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Retinal Artery / Retinaldehyde / Blood Coagulation Tests / Blood Coagulation Factors / Protein C / Visual Acuity / Antithrombin III / Pupil Disorders / Protein S / Antibodies, Anticardiolipin Limits: Adult / Humans Language: Korean Journal: Journal of the Korean Ophthalmological Society Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Retinal Artery / Retinaldehyde / Blood Coagulation Tests / Blood Coagulation Factors / Protein C / Visual Acuity / Antithrombin III / Pupil Disorders / Protein S / Antibodies, Anticardiolipin Limits: Adult / Humans Language: Korean Journal: Journal of the Korean Ophthalmological Society Year: 2008 Type: Article