A Study on the Clinical and Microbiologic Features of Community-acquired Acute Pyelonephritis for the Recent 5 Years in a University Hospital / 대한신장학회잡지
Korean Journal of Nephrology
;
: 905-913, 2002.
Article
in Korean
| WPRIM
| ID: wpr-133585
ABSTRACT
Purpose:
The clinical features and microbiologic characteristics of acute pyelonephritis (APN) have been changing due to an increased prevalence of chronic disease, overuse and/or misuse of antibiotics and so on. We investigated the causative organisms and their antibiotic sensitivity profile and clinical manifestation with the purpose to suggest a proper empirical therapy of the disease.METHODS:
We analysed the medical records of 246 APN patients older than 15 years who were admitted at Hallym University, Kandong Sacred Heart Hospital from January 1997 to December 2001, excluding hospital-acquired infections.RESULTS:
Patients were 46.2+/-19.0 years old with male female ratio of 1 10.2. The severity score was 4.43+/-1.63 out of 8. The average duration of hospital admission was 6.1+/-2.8 days and all of the cases were cured without a complication such as septic shock or renal abscess. In 133 cases, their etiologic microorganisms were identified, among which E. coli was the most common (91.7%). Antibiotic sensitivity of the isolated E. coli strains were as follows; 29.8% to ampicillin, 44.2% to trimethoprim/sulfamethoxazol, 75% to ciprofloxacin, 86.8% to cefazolin and 99.2% to amikacin.CONCLUSION:
E. coli was the most common pathogen of community-acquired APN. Ampicillin, trimethoprim/sulfamethoxazol and cephalothin are inappropriate for its empirical therapy. Ciprofloxacin, 3rd generation cephalosporins and aminoglycosides are effective as the first-line empirical agent.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pyelonephritis
/
Shock, Septic
/
Amikacin
/
Ciprofloxacin
/
Cefazolin
/
Cephalosporins
/
Cephalothin
/
Medical Records
/
Chronic Disease
/
Prevalence
Type of study:
Prevalence study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2002
Type:
Article
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