Long-term Results of Endoscopic Deflux(R) Injection for Vesicoureteral Reflux in Children
Childhood Kidney Diseases
;
: 31-38, 2015.
Article
in English
| WPRIM
| ID: wpr-133632
ABSTRACT
PURPOSE:
We evaluated the long-term results of endoscopic Deflux(R) injection for treating vesicoureteral reflux (VUR) in children.METHODS:
Between September 2004 and September 2014, 243 children (137 boys and 106 girls) with a mean age of 53 months underwent Deflux(R) injection. Our clinical protocol included radionuclide voiding cystography (RNC) at postoperative 3 months, 1 year and 3 years to assess the VUR resolution.RESULTS:
The cure rates at 3 months, 1 year, and 3 years by patients were 70.8%, 64.3%, and 65.6% for the total patients and 79.2%, 75.2%, and 76.4%, for the ureters, respectively. The recurrence rate of postoperative febrile urinary tract infection (UTI) was 20% in patients without VUR at postoperative 1 year. Twenty patients undergoing ureteroneocystostomy (UNC) significantly had younger age (P=0.003), higher VUR grade (P<0.001), and lower success rates of Deflux(R) injection (P<0.05). On univariate analysis, older age (P=0.014) and lower grade of VUR (P=0.031) were the significant predictors of a successful outcome. But there was none on multivariate analysis. Younger age, especially age of 0-12 month-old, was the only significant predictor of postoperative febrile UTI recurrence on both univariate and multivariate analysis.CONCLUSION:
Deflux(R) injection is efficacious with a low complication rate for the anti-reflux procedure in children. There is low recurrence rate of UTI though VUR persists, and high probability of no VUR at 3 years if no VUR at 1 year. It is recommendable not to perform follow-up RNC at 3 years routinely if no VUR at 1 year.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Ureter
/
Urinary Tract Infections
/
Vesico-Ureteral Reflux
/
Clinical Protocols
/
Multivariate Analysis
Type of study:
Practice guideline
/
Prognostic study
Limits:
Child
/
Humans
Language:
English
Journal:
Childhood Kidney Diseases
Year:
2015
Type:
Article
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