Trend for Treatment of Helicobacter pylori in Overseas Country
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
;
: 224-231, 2012.
Article
in Korean
| WPRIM
| ID: wpr-134407
ABSTRACT
Management of Helicobacter pylori infection is still a challenging matter. The aim of eradication of H. pylori is to cure peptic ulcer and decrease the risk of gastric cancer. The prevalence of H. pylori infection is high in developing countries and the burden of gastric cancer in developing countries is large since H. pylori has the potential to increase the risk of gastric cancer. Over the past decade, the efficacy of the standard first-line triple therapy has declined and increased resistance to antibiotics, especially clarithromycin, is considered the most important cause. Attempts to overcome eradication failure have been made. Sequential therapy, quadruple therapy and various combinations of new (quinolone or rifabutin) and old antibiotics have been introduced. This review will give an overview on the dramatic fall in eradication rates all over the world and introduce newer attempts providing promising results.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptic Ulcer
/
Stomach Neoplasms
/
Drug Resistance, Microbial
/
Prevalence
/
Helicobacter pylori
/
Helicobacter
/
Clarithromycin
/
Developing Countries
/
Anti-Bacterial Agents
Type of study:
Prevalence study
Language:
Korean
Journal:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Year:
2012
Type:
Article
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