Increasing Frequency and Burden of Cerebral Artery Atherosclerosis in Korean Stroke Patients
Yonsei Medical Journal
;
: 318-325, 2010.
Article
in English
| WPRIM
| ID: wpr-134521
ABSTRACT
PURPOSE:
Koreans have been undergoing rapid lifestyle changes that may have an effect on patterns of cerebral artery atherosclerosis. This study was aimed at determining the frequency and distribution of atherosclerosis in the cerebral arteries and associated temporal changes over the past eight-year period among Korean stroke patients. MATERIALS ANDMETHODS:
By using stroke registry data registered between April 1999 and March 2007, we investigated the presence, severity, and location of cerebral artery atherosclerosis as determined by angiographic findings. Their annual patterns and association with vascular risk factors were investigated.RESULTS:
Of 1,955 patients, 1,517 patients (77.6%) demonstrated atherosclerosis in one or more arteries. A significantly increasing trend of atherosclerosis was observed during the past eight years, which was ascribed to an increase of combined extracranial (EC) and intracranial (IC) atherosclerosis. The number of atherosclerotic arteries increased as the number of risk factors increased. In the multivariate analysis, the year and vascular risk factors were independent predictors of the presence of atherosclerosis.CONCLUSION:
We found that the atherosclerotic burden has been increasing for the past eight years in Korean stroke patients, particularly the combined EC and IC subtype. Lifestyle changes and increase in vascular risk factors may be contributing factors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Intracranial Arteriosclerosis
/
Multivariate Analysis
/
Risk Factors
/
Age Factors
/
Cost of Illness
/
Asian People
/
Diabetes Mellitus
/
Hypertension
/
Korea
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Yonsei Medical Journal
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS