A Case of Rituximab Use in Rheumatoid Arthritis Following Anti-TNF-Associated Tuberculosis
Journal of Rheumatic Diseases
;
: 100-103, 2012.
Article
in Korean
| WPRIM
| ID: wpr-135254
ABSTRACT
Rituximab has been shown to be effective in rheumatoid arthritis (RA) and is recommended for patients exhibiting an inadequate response to tumor necrosis factor (TNF) inhibitors. To date, there have been no reports of tuberculosis in RA patients treated with rituximab. We report the use of rituximab in a TNF inhibitor-refractory RA patient who had developed tuberculosis. A 52-year-old man with RA had been treated with adalimumab for 3 months, but failed to respond well to the treatment. He reported fever, coughing, sputum, and weight loss. He was diagnosed with pulmonary tuberculosis and started anti-tuberculosis medication. His arthritis was not controlled for despite increasing the dose of prednisolone. He was treated with rituximab without serious adverse effects. Sixteen weeks later, he demonstrated improvement with both arthritis and tuberculosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arthritis
/
Arthritis, Rheumatoid
/
Sputum
/
Tuberculosis
/
Tuberculosis, Pulmonary
/
Prednisolone
/
Weight Loss
/
Tumor Necrosis Factor-alpha
/
Cough
/
Antibodies, Monoclonal, Murine-Derived
Limits:
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2012
Type:
Article
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