The Spot Sign Predicts Hematoma Expansion, Outcome, and Mortality in Patients with Primary Intracerebral Hemorrhage
Journal of Korean Neurosurgical Society
;
: 303-309, 2014.
Article
in English
| WPRIM
| ID: wpr-13566
ABSTRACT
OBJECTIVE:
The purpose of this study was to retrospectively review cases of intracerebral hemorrhage (ICH) medically treated at our institution to determine if the CT angiography (CTA) 'spot sign' predicts in-hospital mortality and clinical outcome at 3 months in patients with spontaneous ICH.METHODS:
We conducted a retrospective review of all consecutive patients who were admitted to the department of neurosurgery. Clinical data of patients with ICH were collected by 2 neurosurgeons blinded to the radiological data and at the 90-day follow-up.RESULTS:
Multivariate logistic regression analysis identified predictors of poor outcome; we found that hematoma location, spot sign, and intraventricular hemorrhage were independent predictors of poor outcome. In-hospital mortality was 57.4% (35 of 61) in the CTA spot-sign positive group versus 7.9% (10 of 126) in the CTA spot-sign negative group. In multivariate logistic analysis, we found that presence of spot sign and presence of volume expansion were independent predictors for the in-hospital mortality of ICH.CONCLUSION:
The spot sign is a strong independent predictor of hematoma expansion, mortality, and poor clinical outcome in primary ICH. In this study, we emphasized the importance of hematoma expansion as a therapeutic target in both clinical practice and research.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Angiography
/
Logistic Models
/
Cerebral Hemorrhage
/
Retrospective Studies
/
Follow-Up Studies
/
Mortality
/
Hospital Mortality
/
Hematoma
/
Hemorrhage
/
Neurosurgery
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2014
Type:
Article
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