Retrospective Study of Oral Antifungal Agents in the Treatment of Toenail Onychomycosis / 대한의진균학회지
Korean Journal of Medical Mycology
;
: 149-154, 2002.
Article
in Korean
| WPRIM
| ID: wpr-135777
ABSTRACT
BACKGROUND:
Clinical success rate is determined by patients compliance which depends on treatment method and period. Retrospective study to clinical success rate may give the information to promote compliance with oral medications for onychomycosis.OBJECTIVE:
The purpose of this study was to evaluate clinical success rate in the different treatment group.METHOD:
For the retrospective study, 618 patients diagnosed clinically and mycologically as having onychomycosis were evaluated for the cure rate and drop-out rate.RESULTS:
The drop-out rate was 31.5% in itraconazole monthly pulse group, 74.3% in itraconazole daily continuous group, 77.5% in terbinafine daily continuous group and 97.8% in fluconazole weekly pulse group. Therefore the success rate was 68.5% in itraconazole monthly pulse group, 25.7% in itraconazole daily continuous group, 22.5% in terbinafine daily continuous group and 2.2% in fluconazole weekly pulse group. The drop-out rate was high in the first period of treatment schedule in most of treatment groups except itraconazole monthly pulse and daily continuous groups.CONCLUSION:
We concluded that the treatment duration and method are the critical factor to treat tonail onychomycosis relating in determining patients' preference for treatment schedules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Appointments and Schedules
/
Fluconazole
/
Retrospective Studies
/
Patient Compliance
/
Onychomycosis
/
Itraconazole
/
Compliance
/
Antifungal Agents
/
Nails
Type of study:
Observational study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Medical Mycology
Year:
2002
Type:
Article
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