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A Case of Extramammary Paget's Disease Treated with 5% Imiquimod Cream / 대한피부과학회지
Korean Journal of Dermatology ; : 365-368, 2006.
Article in Korean | WPRIM | ID: wpr-136877
ABSTRACT
Extramammary Paget's disease (EMPD) is a rare intraepidermal adenocarcinoma. Mohs micrographic surgery is considered the standard treatment. Other treatment modalities such as surgical excision, radiotherapy, topical chemotherapy, and photodynamic therapy are associated with varying degrees of effectiveness, and possible loss of tissue function and disease recurrence are seen. The search for an effective, safe treatment with minimal side effects proves to be challenging. Imiquimod is the first representative of a new class of immunomodulating drugs demonstrating potent antiviral and antitumor activity, and has been approved by the FDA for treating anogenital warts, actinic keratosis and basal cell carcinoma. Recent research has demonstrated its effective usage as a 5% cream in the management of EMPD. We report a case of EMPD of the scrotum successfully treated with topical 5% imiquimod cream. This has never been published in the Korea dermatologic literature.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Photochemotherapy / Radiotherapy / Recurrence / Scrotum / Warts / Carcinoma, Basal Cell / Adenocarcinoma / Mohs Surgery / Paget Disease, Extramammary / Drug Therapy Country/Region as subject: Asia Language: Korean Journal: Korean Journal of Dermatology Year: 2006 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Photochemotherapy / Radiotherapy / Recurrence / Scrotum / Warts / Carcinoma, Basal Cell / Adenocarcinoma / Mohs Surgery / Paget Disease, Extramammary / Drug Therapy Country/Region as subject: Asia Language: Korean Journal: Korean Journal of Dermatology Year: 2006 Type: Article