Effect of Levothyroxine Treatment on Clinical Symptoms in Hypothyroid Patients with Chronic Urticaria and Thyroid Autoimmunity
Annals of Dermatology
;
: 199-204, 2016.
Article
in English
| WPRIM
| ID: wpr-136941
ABSTRACT
BACKGROUND:
Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria (CU), and the possible clinical benefit of thyroid hormone or anti-thyroid drugs in some CU patients with autoimmune thyroid disease has been studied. However, the effect of thyroid hormone or anti-thyroid drugs on clinical symptoms of CU remains unclear.OBJECTIVE:
We investigated the clinical response of urticaria to the treatment of thyroid dysfunction.METHODS:
Medical records of patients with CU evaluated for thyroid autoimmunity and thyroid function were collected and reviewed.RESULTS:
Of 184 patients with CU, 43 patients (23.4%) had thyroid autoantibodies and 26 patients (14.1%) had thyroid dysfunction. While none of the five patients with Graves' disease showed any improvement of urticaria after treatment with anti-thyroid drugs, two of the 10 patients with Hashimoto's thyroiditis showed improved urticaria after being treated with levothyroxine.CONCLUSION:
Although levothyroxine treatment was effective in a minority of patients with CU, there may be a causal relationship between CU and thyroid autoimmunity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autoantibodies
/
Thyroid Diseases
/
Thyroid Gland
/
Thyroiditis
/
Thyroxine
/
Urticaria
/
Autoimmunity
/
Graves Disease
/
Medical Records
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Annals of Dermatology
Year:
2016
Type:
Article
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