The optimal concentrations of propofol at eye opening and orientation after propofol-remifentanil TCI in Koreans
Anesthesia and Pain Medicine
;
: 131-137, 2011.
Article
in English
| WPRIM
| ID: wpr-136950
ABSTRACT
BACKGROUND:
The recovery time in propofol target controlled infusion (TCI) can be determined by the context sensitive decrement time (CSDT) using a Multichannel TCI system. Therefore, it is important to obtain the default CSDT in a Multichannel TCI system. The effect-site concentrations for eye opening and orientation in adults after propofol-remifentanil TCI were evaluated according to the CSDT using a Multichannel TCI system.METHODS:
After obtaining informed consent and Institutional Review Board approval, 135 ASA Class I or II patients scheduled to undergo elective surgery were divided into 3 groups according to age. The three groups included the following group 1 (n = 45), 18-19 years; group 2 (n = 45), 30-39 years; and group 3 (n = 45), 40-54 years. The propofol infusion was started at a propofol target effect-site concentration (CeT) of 6microg/ml. Anesthesia was maintained primarily with a propofol CeT of 2.5microg/ml, a remifentanil CeT of 6ng/ml and with 67% nitrous oxide in oxygen. The average effect-site concentrations of propofol at eye opening and orientation in each group were estimated.RESULTS:
The average range of the effect-site concentrations of propofol at eye opening and orientation after surgery were 0.9-1.1microg/ml. The range of times to eye opening and orientation after stopping the nitrous oxide and infusion after surgery were 10.9-12.9 min.CONCLUSIONS:
The average range of the effect-site concentrations of propofol at eye opening and orientation after propofol-remifentanil TCI in Koreans are 0.9-1.1microg/ml.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orientation
/
Oxygen
/
Piperidines
/
Propofol
/
Ethics Committees, Research
/
Eye
/
Informed Consent
/
Anesthesia
/
Anesthesia, Intravenous
/
Nitrous Oxide
Limits:
Adult
/
Humans
Language:
English
Journal:
Anesthesia and Pain Medicine
Year:
2011
Type:
Article
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