Comparison of Response between the Ulnar , Facial , Peroneal and Tibial Nerve after Administration of Vecuronium / 대한마취과학회지

ABSTRACT

Since as neuromuscular blocking agents are usually used during general anesthesia, monitoring of muscle relaxation is integra1 part of the management of patients and the ulnar nerve is allowed commonly to evaluate of neuromuscu1ar blockade. But our study was designed to monitor neuromuscular blockade-induced Vecuronium blocakade in 40 ASA 1-2 adult pateints in various nerves other than ulnar nerve with the single twitch(T1) and post-tetanic count(PTC) methods. All patients were premedicated with glycopyrrolate 0.2 mg and hydroxizine 1 mg/kg Ihour before induction, and were inducted with thiopental sodium 5 mg/kg and maintained with nitrous oxide(50%) and enflurane(1-2%). The patients were randomly divided to 4 groups, the ulnar nerve group was monitored at the adductor pollicis muscle, the facial nerve group was monitored at the orbicularis oculi muscle, the peroneal nerve group was monitored at the extensor digitorum brevis muscle, and the tibial nerve group was monitored at the flexor hallucis brevis muscle. After administration of vecuronium bromide 0.1 mg/kg, the onset time, duration of action and recovery time were compared between 4 group by INNERVATOR(Fisher & Paykel Co). The results obtained were as follow; 1) At the onset time, the facial nerve group was significant shorter than the ulnar nerve group, but the tibial and peroneal nerve group was significant prolonged. 2) The action duration from disappearance of single twitch to first appearance of PTC was significant prolonged in the peroneal nerve group than the ulnar nerve group but no significance was observed in the facial and tibial nerve gruop. 3) The recovery time from disappearance of single twitch to first appearance of single twitch was significant prolonged in the peroneal nerve group than the ulnar nerve group but no significance was observed in the facial and tibial nerve group.