Jugulotympanic Paraganglioma, Mimicking a Vascular Tumor: A Brief Case Report
Korean Journal of Pathology
;
: 543-546, 2010.
Article
in English
| WPRIM
| ID: wpr-138449
ABSTRACT
Jugulotympanic paragangliomas (JTPs) known as glomus tumors, are neoplasms of variable invasiveness that arise from the paraganglia situated around the jugular bulb or middle ear. We now report a rare case of JTP in an 18-year-old male. Preoperative diagnoses through external auditory canal biopsy and radiologic examination both failed. Even using a frozen section, an informative finding was not obtained because mostly granulation tissue was present along with associated squeezing artifacts. On permanent histologic examination, small cell nests between many ectatic small vessels and fibrotic stroma were seen, and those cells were positive for CD56, synaptophysin and chromogranin. Because JTPs are rare and have rather different histologic findings - higher vascularity, smaller and less uniform tumor cells than other paragangliomas - they are easy to misdiagnose. However, remembering those differences may help the physician avoid missing JTPs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paraganglioma
/
Biopsy
/
Synaptophysin
/
Artifacts
/
Glomus Tumor
/
Paraganglioma, Extra-Adrenal
/
Glomus Tympanicum
/
Ear Canal
/
Ear, Middle
/
Frozen Sections
Limits:
Adolescent
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Pathology
Year:
2010
Type:
Article
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