Multivessel Thromboembolism Associated with Dysfunction of Protein S
Annals of Rehabilitation Medicine
;
: 414-417, 2012.
Article
in English
| WPRIM
| ID: wpr-138765
ABSTRACT
Protein S is a vitamin K-dependent coagulation factor that acts as an anticoagulant. Deficiency of protein S increases the risk of thromboembolic events. We report a case of isolated protein S deficiency in a 39-year-old woman suffering arterial occlusion in both lower legs. She underwent a surgical procedure using thrombectomy and balloon angioplasty of her left lower extremity. Later, she had right trans-tibial amputation because of the reperfusion injury. Throughout the evaluation of thromboembolic events, we diagnosed a large thrombus in the right atrium and an asymptomatic pulmonary thromboembolism. The patient was successfully treated with right atrial thrombectomy and systemic anticoagulation. Careful evaluation for protein S levels may be necessary in patients with arterial thromboembolic events, especially young adults.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pulmonary Embolism
/
Stress, Psychological
/
Thromboembolism
/
Thrombosis
/
Vitamins
/
Blood Coagulation Factors
/
Reperfusion Injury
/
Thrombectomy
/
Protein S
/
Angioplasty, Balloon
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Annals of Rehabilitation Medicine
Year:
2012
Type:
Article
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