Risk Factors of Non-alcoholic Steatohepatitis in Childhood Obesity / 대한소아소화기영양학회지
Korean Journal of Pediatric Gastroenterology and Nutrition
;
: 179-184, 2007.
Article
in Korean
| WPRIM
| ID: wpr-139408
ABSTRACT
PURPOSE:
Obesity has recently emerged as a significant health problem in the pediatric population, and the prevalence of non-alcoholic fatty liver disease is increasing in tandem with a significant rise in childhood obesity. Therefore, this study was conducted to clarify the risk factors of non-alcoholic steatohepatitis in obese children.METHODS:
We enrolled 84 obese children who visited the pediatric obesity clinic at Yeung-Nam university hospital. The patients were divided into two groups based on their alanine aminotransferase (ALT) level (separated at 40 IU/L), and the mean of ages, total cholesterol levels, HDL-cholesterol levels, LDL-cholesterol levels, triglyceride (TG) levels, as well as the mean obesity index, and body fat percentage of the two groups were then compared.RESULTS:
When the mean of ages (10.5+/-1.6 vs. 10.7+/-2.0 years), total cholesterol levels (183.0+/-29.1 vs. 183.7+/-31.3 mg/dL), HDL-cholesterol levels (53.0+/-10.2 vs. 55.7+/-13.0 mg/dL), LDL-cholesterol levels (113.4+/-30.2 vs. 113.0+/-30.0 mg/dL), triglyceride levels (99.4+/-62.9 vs. 114.2+/-47.3 mg/dL), obesity indexes (44.7+/-12.2 vs. 47.9+/-15.1%), and body fat percentages (32.7+/-5.0 vs. 34.0+/-4.8%) of group 1 (ALT or =41 IU/L), no significant differences were observed (p>0.05). However, hypertriglyceridemia (TG> or =110 mg/dL) was more frequent in group 2 than in group 1 (p=0.023).CONCLUSION:
TG may be an important risk factor in non-alcoholic steatohepatitis and further study regarding the risk factors in non-alcoholic steatohepatitis is required.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Triglycerides
/
Hypertriglyceridemia
/
Adipose Tissue
/
Cholesterol
/
Prevalence
/
Risk Factors
/
Alanine Transaminase
/
Fatty Liver
/
Pediatric Obesity
/
Obesity
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Pediatric Gastroenterology and Nutrition
Year:
2007
Type:
Article
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