Nephrotic syndrome associated with early neurosyphilis / 대한내과학회지
Korean Journal of Medicine
;
: S162-S167, 2009.
Article
in Korean
| WPRIM
| ID: wpr-139809
ABSTRACT
Nephrotic syndrome, hepatitis, and CNS involvement resulting from secondary syphilis are well-documented complications of neurosyphilis. However, the simultaneous occurrence of these complications is rare. The present report describes a 49-year-old male with early neurosyphilis who presented with features of nephritic syndrome and hepatitis. A diagnosis of neurosyphilis was made by CSF study and serologic tests. After the diagnosis of neurosyphilis, nephrotic syndrome and hepatitis were suspected to be factors of the neurosyphilis. A kidney biopsy revealed membranous nephropathy characterized by subepithelial electron dense deposits and diffuse effacement of foot processes. Abdominal ultrasonography showed hepatitis. The patient was treated with intravenous potassium penicillin G, 4 million units for 2 weeks, and the symptoms and signs resolved after the penicillin therapy. In conclusion, complications experienced by patients with a history of syphilis or syphilis lesions need to be minimized through careful observations and multi-organ treatments.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Penicillin G
/
Penicillins
/
Potassium
/
Biopsy
/
Serologic Tests
/
Glomerulonephritis, Membranous
/
Syphilis
/
Electrons
/
Foot
/
Hepatitis
Type of study:
Diagnostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2009
Type:
Article
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