Volumetric measurement of the inflamed synovium of rheumatoid wrist joint for the evaluation of synovitis and remission
Journal of the Korean Radiological Society
;
: 509-515, 1997.
Article
in Korean
| WPRIM
| ID: wpr-140000
ABSTRACT
PURPOSE:
To evaluate the changes and remission of disease activity with changes in inflamed synivial volumes of rheumatoid joints after therapy. MATERIALS ANDMETHODS:
Seven rheumatoid arthritis patients who had been treated with antiinflammatory drugs were followed up. Using NIH imaging and a segmentation technique, pre- and post-enhanced images were measured in subtracted images. Intra- and interobserver variation were evaluated by two radiologists(A and B), using two independent measurements. For comparison, the cases were assigned to one of two groups remission and non-remission. Changes in ESR and total joint counts(TJC) after therapy were compared with inflamed synovial volumes.RESULTS:
Intraobserver variations were 3.2% and 2.7% in A and B, respectively, interobserver variation between A and B was 7.1%. Changes in inflamed synovial volumes correlated well with those in ESR (r=0.88, p<0.009) and TJC (r=0.78, p<0.037) after therapy. Changes between the remission and non-remission group were insignificant, however.CONCLUSION:
Changes in inflamed synovial volumes reflect those in the activity of rheumatoid arthritis between pre- and post- treatment. This technique may be used as a tool for predicting therapeutic response in rheumatoid arthritis cases. Changes in inflamed synovial volumes are of limited value, however, in predicting the remission of rheumatoid arthritis after therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arthritis, Rheumatoid
/
Synovial Membrane
/
Synovitis
/
Wrist
/
Wrist Joint
/
Observer Variation
/
Joints
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Radiological Society
Year:
1997
Type:
Article
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