Chemical Constituents from the Aerial Parts of Bupleurum falcatum L. and Biological Evidences
Natural Product Sciences
;
: 71-75, 2015.
Article
in English
| WPRIM
| ID: wpr-14018
ABSTRACT
In this study, phytochemical investigation on the aerial parts of Bupleurum falcatum resulted in the isolation of fourteen compounds including three quinic acid derivatives (1 - 3), five flavonoids (4 - 8), three monoterpene glycosides (9 - 11), and three saikosaponins (12 - 14). Compound 1 was first isolated from nature and unambiguously determined to be 3-O-feruloyl 5-O-caffeoylquinic acid on the basis of the extensive spectroscopic evidence. Biological testing revealed that saikosaponin A (12) and saikosaponin D (13) showed moderate antiproliferative effects on HL-60 and HepG2 cancer cell lines.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quinic Acid
/
Flavonoids
/
Cell Line
/
Bupleurum
/
Glycosides
Language:
English
Journal:
Natural Product Sciences
Year:
2015
Type:
Article
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