The Expressions of Matrix Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinase-1 in Scar Endometriosis and Full Term Endometrium / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 1311-1316, 2002.
Article
in Korean
| WPRIM
| ID: wpr-140937
ABSTRACT
OBJECTIVE:
Endometriosis in a surgical scar following cesarian section is rare condition. And its pathogenesis has not been well established. The purpose of this study is to observe the expressions of matrix metalloproteinase-9 (MMP-9) and tissue inhibitors of metalloproteinase-1 (TIMP-1) in scar endometriosis and full term endometrium during cesarian section.METHODS:
Nineteen scar endometriotic tissue and ten full term pregnant endometrium during cesarian section were investigated by immunohistochemical stain for MMP-9 and TIMP-1.RESULTS:
The MMP-9 was expressed in eleven of nineteen scar endometriotic tissue (57.9%) and eight of ten full term pregnant endometrium (80.0%). The TIMP-1 was not expressed in both scar endometriotic tissue and full term pregnant endometrium.CONCLUSION:
These results suggest that the relationship between MMP-9 and TIMP-1 might play a role of pathogenesis of scar endometriosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cicatrix
/
Tissue Inhibitor of Metalloproteinase-1
/
Matrix Metalloproteinase 9
/
Endometriosis
/
Endometrium
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2002
Type:
Article
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