Dedifferentiated Extraskeletal Myxoid Chondrosarcoma of the Masticator Space: A Case Report
Korean Journal of Pathology
;
: S101-S105, 2011.
Article
in English
| WPRIM
| ID: wpr-140939
ABSTRACT
We describe a 69-year-old woman who presented with a dedifferentiated extraskeletal myxoid chondrosarcoma arising in the left masticator space. Computed tomography and magnetic resonance imaging revealed a 5 cm sized mass in the left masticator space. Histologically, the tumor consisted of two distinct areas. The less cellular area was a low-grade extraskeletal myxoid chondrosarcoma, composed of strands or cords of uniform spindle cells and abundant myxoid stroma. The more cellular, dedifferentiated area corresponded to a high grade myxofibrosarcoma, consisting of anaplastic tumor cells in myxoid stroma and geographic necrosis. The tumor cells of the former area were positive for S-100 protein, microtubule-associated protein-2 (MAP-2) and class III beta-tubulin, but negative for cytokeratin, smooth muscle actin, and desmin. The tumor cells in the latter, pleomorphic area showed MAP-2 and beta-tubulin immunoreactivity with a high Ki-67 labeling index. Based on its histologic and immunohistochemical features, the tumor was considered a dedifferentiated extraskeletal myxoid chondrosarcoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tubulin
/
Magnetic Resonance Imaging
/
S100 Proteins
/
Chondrosarcoma
/
Actins
/
Desmin
/
Cell Dedifferentiation
/
Keratins
/
Muscle, Smooth
/
Necrosis
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Korean Journal of Pathology
Year:
2011
Type:
Article
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