Effect of Bovine and Human Lactoferrin on MA 104 Cell Infected with Human Rotavirus
Journal of the Korean Society of Virology
;
: 87-97, 1999.
Article
in Korean
| WPRIM
| ID: wpr-142037
ABSTRACT
It has long been known that lactoferrin prevents human beings from infection of virus. To prove this activity of lactoferrin, we evaluated the activities of different lactoferrins to an isolate human rotavirus K-21. Bovine lactoferrin inhibited infection of K-21 to MA-104 cell at the concentration of 25.9 microM whereas bovine hydrolysed lactoferrin prevented rotavirus infection at 103.8 microM. However human lactoferrin prevented infection of K-21 at the concentration of 217.5 microM. These data suggested that lactoferrin activity may be unaffected by the intestinal digestive enzymes and bovine lactoferrin is more active than human lactoferrin with respect to prevention of rotavirus infection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rotavirus Infections
/
Rotavirus
/
Lactoferrin
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Society of Virology
Year:
1999
Type:
Article
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