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A Case of Congenital Acute Megakaryoblastic Leukemia with Down Syndrome
Journal of the Korean Pediatric Society ; : 578-583, 1997.
Article in Korean | WPRIM | ID: wpr-142150
ABSTRACT
We experienced a case of congenital acute megakaryoblastic leukemia with Down syndrome. The patient was admitted due to characteristic facial figure of Down syndrome and abdominal distension. Acute megakaryoblastic leukemia was diagnosed with abundant megakaryoblast in peripheral blood smear, severe myelofibrosis in bone marrow biopsy and positive platelet glycoprotein III a receptor. On third hospital day, the patient expired due to DIC and pulmonary hemorrhage. Authors report the case with review of literature.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Biopsy / Blood Platelets / Bone Marrow / Glycoproteins / Leukemia, Megakaryoblastic, Acute / Down Syndrome / Dacarbazine / Megakaryocyte Progenitor Cells / Primary Myelofibrosis / Hemorrhage Limits: Humans Language: Korean Journal: Journal of the Korean Pediatric Society Year: 1997 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Biopsy / Blood Platelets / Bone Marrow / Glycoproteins / Leukemia, Megakaryoblastic, Acute / Down Syndrome / Dacarbazine / Megakaryocyte Progenitor Cells / Primary Myelofibrosis / Hemorrhage Limits: Humans Language: Korean Journal: Journal of the Korean Pediatric Society Year: 1997 Type: Article