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Endoscopic Management of Bile Leakage after Liver Transplantation
Gut and Liver ; : 417-423, 2015.
Article in English | WPRIM | ID: wpr-142458
ABSTRACT
BACKGROUND/

AIMS:

Endoscopic retrograde cholangiopancreatography (ERCP) can be an effective treatment for bile leakage after liver transplantation. We evaluated the efficacy of endoscopic treatment in liver transplantation in patients who developed bile leaks.

METHODS:

Forty-two patients who developed bile leaks after liver transplantation were included in the study. If a bile leak was observed on ERCP, a sphincterotomy was performed, and a nasobiliary catheter was then inserted. If a bile leak was accompanied by a bile duct stricture, either the stricture was dilated with balloons, followed by nasobiliary catheter insertion across the bile duct stricture, or endoscopic retrograde biliary drainage was performed.

RESULTS:

In the bile leakage alone group (22 patients), endoscopic treatment was technically successful in 19 (86.4%) and clinically successful in 17 (77.3%) cases. Among the 20 patients with bile leaks with bile duct strictures, endoscopic treatment was technically successful in 13 (65.0%) and clinically successful in 10 (50.0%) cases. Among the 42 patients who underwent ERCP, technical success was achieved in 32 (76.2%) cases and clinical success was achieved in 27 (64.3%) cases.

CONCLUSIONS:

ERCP is an effective and safe therapeutic modality for bile leaks after liver transplantation. ERCP should be considered as an initial therapeutic modality in post-liver transplantation patients.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Bile / Biliary Tract Diseases / Stents / Drainage / Cholangiopancreatography, Endoscopic Retrograde / Liver Transplantation / Treatment Outcome / Constriction, Pathologic / Anastomotic Leak Limits: Adult / Female / Humans / Male Language: English Journal: Gut and Liver Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Bile / Biliary Tract Diseases / Stents / Drainage / Cholangiopancreatography, Endoscopic Retrograde / Liver Transplantation / Treatment Outcome / Constriction, Pathologic / Anastomotic Leak Limits: Adult / Female / Humans / Male Language: English Journal: Gut and Liver Year: 2015 Type: Article