A Case of Chronic Granulomatous Disease Which is Improved by Interferon- Therapy
Journal of the Korean Pediatric Society
;
: 1021-1025, 1997.
Article
in Korean
| WPRIM
| ID: wpr-14259
ABSTRACT
Chronic granulomatous disease is a group of rare disorders characterized by a disease of oxidative metabolism of phagocytes with deficit of antimicrobial activity. Also, it has clinical features of chronic pyogenic infection, granuloma formation, hypergammaglobulinemia, anemia and leukocytosis.We experienced a case of chronic granulomatous disease with chronic recurrent infection, hypergammaglobulinemia and liver abscess. It was confirmed by modified NBT test. The result of patient's NBT test was less than 11%. The patient received subcutaneous injection of interferon-gamma, 200 million unit (0.1mg/m2 of body surface area per dose), on three consecutive days per week for 3 weeks and her symptom was improved. Then, we report a case of chronic granulomatous disease which is improved by interferon- therapy with brief review of literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phagocytes
/
Body Surface Area
/
Interferon-gamma
/
Granuloma
/
Granulomatous Disease, Chronic
/
Hypergammaglobulinemia
/
Injections, Subcutaneous
/
Anemia
/
Liver Abscess
/
Metabolism
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Pediatric Society
Year:
1997
Type:
Article
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