A Case of Rifampin Induced Hemolytic Anemia Combined with Thrombocytopenia and Acute Renal Failure / 대한수혈학회지
Korean Journal of Blood Transfusion
;
: 56-60, 2007.
Article
in Korean
| WPRIM
| ID: wpr-14264
ABSTRACT
A 35 year old woman was admitted to the hospital owing to her nausea, vomiting, oliguria and petechia with re-administration of rifampin. Laboratory tests were performed and they showed a hemoglobin level of 8.6 g/dL, a leukocyte count of 7,660/microliter, a platelet count of 1,000/microliter, a blood urea nitrogen level of 92.3 mg/dL and a creatinine level of 10.6 mg/dL. The Direct Coombs' test and anti-platelet antibody test were positive. Hemolytic anemia combined with thrombocytopenia and acute renal failure related to rifampin was suspected. We proved the formation of immune complex with anti-rifampin antibody and rifampin by in vitro testing. Hemolytic anemia combined with thrombocytopenia and acute renal failure after treatment with rifampin is a rare condition. We report here on such a case along with a brief review of the related literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oliguria
/
Platelet Count
/
Rifampin
/
Thrombocytopenia
/
Vomiting
/
Blood Urea Nitrogen
/
Coombs Test
/
Creatinine
/
Acute Kidney Injury
/
Anemia, Hemolytic
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Blood Transfusion
Year:
2007
Type:
Article
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