Epidemiology of astrovirus infection in children / 소아과
Korean Journal of Pediatrics
;
: 77-82, 2012.
Article
in English
| WPRIM
| ID: wpr-143973
ABSTRACT
Human astrovirus (HAstV) is a major cause of acute diarrhea among children, resulting in outbreaks of diarrhea and occasionally hospitalization. Improved surveillance and application of sensitive molecular diagnostics have further defined the impact of HAstV infections in children. These studies have shown that HAstV infections are clinically milder (diarrhea, vomiting, fever) than infections with other enteric agents. Among the 8 serotypes of HAstV identified, serotype 1 is the predominant strain worldwide. In addition to serotype 1, the detection rate of HAstV types 2 to 8 has increased by using newly developed assays. HAstV is less common compared with other major gastroenteritis viruses, including norovirus and rotavirus; however, it is a potentially important viral etiological agent with a significant role in acute gastroenteritis. A better understanding of the molecular epidemiology and characteristics of HAstV strains may be valuable to develop specific prevention strategies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Mamastrovirus
/
Sprains and Strains
/
Vomiting
/
Disease Outbreaks
/
Molecular Epidemiology
/
Norovirus
/
Diarrhea
/
Pathology, Molecular
/
Gastroenteritis
/
Hospitalization
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2012
Type:
Article
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