Myopathy With Anti Signal Recognition Particle Antibody
Journal of the Korean Neurological Association
;
: 231-233, 2011.
Article
in Korean
| WPRIM
| ID: wpr-145202
ABSTRACT
Myopathies associated with anti-signal-recognition particle (SRP) antibodies usually present with severe muscle weakness and exhibit necrotizing myopathy with little inflammation pathologically. Here we report a case of a 61-year-old man who presented with subacute progressive proximal muscle weakness, dysarthria, and dysphagia. Although polymyositis was expected clinically, muscle biopsy revealed myopathic changes with degenerating fibers without definite inflammation. Further laboratory study revealed that the patient was positive for anti-SRP antibodies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autoantibodies
/
Biopsy
/
Deglutition Disorders
/
Polymyositis
/
Signal Recognition Particle
/
Muscle Weakness
/
Dysarthria
/
Inflammation
/
Antibodies
/
Muscles
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2011
Type:
Article
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