Clinical Characteristics and Prognosis of Lymphocyte Dominant Exudative Pleural Effusion with Low ADA, Low CEA, Negative Cytology and Negative AFB Smear / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 5-10, 2005.
Article
in Korean
| WPRIM
| ID: wpr-145392
ABSTRACT
BACKGROUND:
A pleural effusion is a common medical problem. Despite several diagnostic tests, 15-20% of pleural effusions go undiagnosed. The aim of this study was to evaluate the clinical characteristics and prognosis of a lymphocyte dominant exudative pleural effusion with a low adenosine deaminase (ADA), low carcinoembryonic antigen (CEA), negative cytology and negative acid fast bacilli (AFB) smear.METHOD:
From Jan 2000 to Aug 2001, 43 patients with lymphocyte dominant exudative pleural effusions whose AFB smear and cytologic exam were negative, their pleural fluid ADA level was < 40 IU/L, and their CEA level was < 10 ng/mL were enrolled in this study. A retrospective analysis of the patients' medical records was carried out.RESULT:
Among 31 of the 43 cases (72%), probable underlying diseases causing the pleural effusion were identified 21cases of malignant diseases, 4 cases of liver cirrhosis, 2 cases of pulmonary tuberculosis, 1 case of end stage renal disease, 1 case of a chylothorax, 1 case of a post?CABG (coronary artery bypass graft) state, 1 case of a pulmonary embolism. No clinically suspected etiology was identified in the remaining 12 cases (28%). Of these 12 pleural effusions, 7 cases spontaneously resolved, 2 effusions resolved with antibiotics, and the other 2 cases were persistent.CONCLUSION:
Lymphocyte dominant exudative pleural effusions with a low ADA, low CEA, negative cytological exam, and negative AFB smear, but without a definite cause might have a benign course and clinicians can observe them with attention.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pleural Effusion
/
Arteries
/
Prognosis
/
Pulmonary Embolism
/
Tuberculosis, Pulmonary
/
Lymphocytes
/
Carcinoembryonic Antigen
/
Adenosine Deaminase
/
Medical Records
/
Retrospective Studies
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Tuberculosis and Respiratory Diseases
Year:
2005
Type:
Article
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