Usefulness of 18F-FDG PET/CT in the Diagnosis of Cervical Lymph Node Metastases of Head and Neck Cancer / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 269-277, 2005.
Article
in Korean
| WPRIM
| ID: wpr-145410
ABSTRACT
PURPOSE:
This study evaluated the diagnostic value of 18F-FDG PET/CT in detecting cervical lymph node metastases in head and neck cancer patients. MATERIALS ANDMETHODS:
The patients were divided into two groups, 46 patients underwent PET/CT scan for initial staging before surgery, and 20 patients for restaging of recurrence after primary treatment. Increased FDG uptakes in cervical lymph nodes were evaluated retrospectively and correlated with the histopathologic results.RESULTS:
In the initial staging group, 21 lymph nodes were detected by PET/CT in 15 patients. 20 lymph nodes were confirmed as metastases with a mean peak SUV of 5.84, and the remaining one lymph node was an inflammatory lesion, with a peak SUV of 2.75. Seven metastatic lymph nodes were reported only by histopathology. The sensitivity, specificity, positive predictive value and negative predictive value were 74.0%, 99.6%, 95.2% and 97.3%, respectively. In the recurrence group, 11 lymph nodes were detected in 9 patients, and 8 nodes were true positive, with a mean peak SUV of 5.65. The other three were inflammatous lymph nodes, and the peak SUVs were 2.16, 2.94 and 3.53. One false negative lymph node was reported. The sensitivity, specificity, positive predictive value and negative predictive value were 88.8%, 97.7%, 72.7% and 92.9%, respectively.CONCLUSIONS:
FDG-PET/CT shows higher positive predictive value in the initial staging group, and better sensitivity in the recurrence group. Therefore PET/CT could be useful for both initial staging and restaging of recurrent cervical lymph node metastases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Retrospective Studies
/
Sensitivity and Specificity
/
Fluorodeoxyglucose F18
/
Diagnosis
/
Positron Emission Tomography Computed Tomography
/
Head
/
Head and Neck Neoplasms
/
Lymph Nodes
/
Neoplasm Metastasis
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nuclear Medicine
Year:
2005
Type:
Article
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