Confronting Practical Problems for Initiation of On-line Hemodiafiltration Therapy
Electrolytes & Blood Pressure
;
: 1-4, 2016.
Article
in English
| WPRIM
| ID: wpr-145687
ABSTRACT
Conventional hemodialysis, which is based on the diffusive transport of solutes, is the most widely used renal replacement therapy. It effectively removes small solutes such as urea and corrects fluid, electrolyte and acid-base imbalance. However, solute diffusion coefficients decreased rapidly as molecular size increased. Because of this, middle and large molecules are not removed effectively and clinical problem such as dialysis amyloidosis might occur. Online hemodiafiltration which is combined by diffusive and convective therapies can overcome such problems by removing effectively middle and large solutes. Online hemodiafiltration is safe, very effective, economically affordable, improving session tolerance and may improve the mortality superior to high flux hemodialysis. However, there might be some potential limitations for setting up online hemodiafiltaration. In this article, we review the uremic toxins associated with dialysis, definition of hemodiafiltration, indication and prescription of hemodiafiltration and the limitations of setting up hemodiafiltration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acid-Base Imbalance
/
Urea
/
Water
/
Mortality
/
Renal Dialysis
/
Renal Replacement Therapy
/
Hemodiafiltration
/
Dialysis
/
Diffusion
/
Prescriptions
Type of study:
Prognostic study
Language:
English
Journal:
Electrolytes & Blood Pressure
Year:
2016
Type:
Article
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