Oocyte Maturity in Relation to Woman's Age in In Vitro Fertilization Cycles Stimulated by Single Regimen
Yonsei Medical Journal
;
: 181-185, 2012.
Article
in English
| WPRIM
| ID: wpr-145834
ABSTRACT
PURPOSE:
During stimulated in vitro fertilization (IVF) cycle, up to 30% of the recovered oocytes are immature ones which have poor fertilization capacity; however, the precise influencing factors are largely unknown. Here, we analyzed the association of oocyte immaturity with woman's age in IVF cycles stimulated by single regimen. MATERIALS ANDMETHODS:
A total of one-hundred ninety five IVF cycles stimulated by recombinant FSH and GnRH antagonist protocol between 2003 and 2009 were analyzed retrospectively. The mean age of women was 34.2+/-4.0 (26-45 years). After triggering by exogenous hCG, an ultrasound-guided retrieval of oocytes was performed 35-36 hours later. All clinical data were stratified by woman's age; group I or =41 (n=19).RESULTS:
The total retrieved oocytes, as well as immature oocytes, were significantly lower in group IV, however, the mean % of immature oocytes was significantly higher in group IV than other age groups. Oocyte immaturity tended to decrease as increasing age in women aged 40 years or less.CONCLUSION:
In stimulated IVF cycle, much higher oocyte immaturity was noted in women aged 41 years or more.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oocytes
/
Ovulation Induction
/
Fertilization in Vitro
/
Retrospective Studies
/
Gonadotropin-Releasing Hormone
/
Age Factors
/
Pregnancy Rate
/
Oocyte Retrieval
/
Follicle Stimulating Hormone
Type of study:
Practice guideline
/
Observational study
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Yonsei Medical Journal
Year:
2012
Type:
Article
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