Permissive Hypotension in Extremely Low Birth Weight Infants (< or =1000 gm)
Yonsei Medical Journal
;
: 765-771, 2012.
Article
in English
| WPRIM
| ID: wpr-14587
ABSTRACT
PURPOSE:
We performed this study to evaluate the safety of permissive hypotension management in extremely low birth weight infants (ELBWIs). MATERIALS ANDMETHODS:
Medical records of all inborn ELBWIs admitted to Samsung Medical Center from January 2004 to December 2008 were reviewed retrospectively. Of a total of 261 ELBWIs, 47 (18%) required treatment for hypotension (group T), 110 (42%) remained normotensive (group N), and 104 (40%) experienced more than one episode of hypotension without treatment (group P) during the first 72 hours of life. Treatment of hypotension included inotropic support and/or fluid loading.RESULTS:
Birth weight and Apgar scores were significantly lower in the T group than the other two groups. In the N group, the rate of pathologically confirmed maternal chorioamnionitis was significantly higher than other two groups, and the rate was higher in the P group than the T group. After adjusting for covariate factors, no significant differences in mortality and major morbidities were found between the N and P groups. However, the mortality rate and the incidence of intraventricular hemorrhage (> or =stage 3) and bronchopulmonary dysplasia (> or =moderate) were significantly higher in the T group than the other two groups. Long term neurodevelopmental outcomes were not significantly different between the N and P groups.CONCLUSION:
Close observation of hypotensive ELBWIs who showed good clinical perfusion signs without intervention allowed to avoid unnecessary medications and resulted in good neurological outcomes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Apgar Score
/
Birth Weight
/
Infant, Extremely Low Birth Weight
/
Hypotension
Type of study:
Prognostic study
Limits:
Female
/
Humans
/
Male
/
Infant, Newborn
Language:
English
Journal:
Yonsei Medical Journal
Year:
2012
Type:
Article
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