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Cortical Laminar Necrosis associated with Osmotic Demyelination Syndrome
Journal of Clinical Neurology ; : 174-176, 2005.
Article in English | WPRIM | ID: wpr-146317
ABSTRACT
Cortical laminar necrosis has been rarely observed in osmotic demyelination syndrome. We report a 32-year-old female patient who became comatose after the rapid correction of hyponatremia. There were high signal intensities in the pons and bilateral deep gray nuclei on T2-weighted MRI images, and linear hyperintensities along the cerebral cortices on T1-weighted images with a diffuse gyriform enhancement. MR spectroscopic findings showed a decrease of the N-acetyl aspartate peak and an increase in those of the lipid and lactate complex. The case demonstrates that a severe form of osmotic demyelination syndrome accompanying cortical laminar necrosis can result from the rapid correction of hyponatremia.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pons / Magnetic Resonance Imaging / Cerebral Cortex / Demyelinating Diseases / Aspartic Acid / Coma / Lactic Acid / Hyponatremia / Necrosis Limits: Adult / Female / Humans Language: English Journal: Journal of Clinical Neurology Year: 2005 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pons / Magnetic Resonance Imaging / Cerebral Cortex / Demyelinating Diseases / Aspartic Acid / Coma / Lactic Acid / Hyponatremia / Necrosis Limits: Adult / Female / Humans Language: English Journal: Journal of Clinical Neurology Year: 2005 Type: Article