Cortical Laminar Necrosis associated with Osmotic Demyelination Syndrome
Journal of Clinical Neurology
;
: 174-176, 2005.
Article
in English
| WPRIM
| ID: wpr-146317
ABSTRACT
Cortical laminar necrosis has been rarely observed in osmotic demyelination syndrome. We report a 32-year-old female patient who became comatose after the rapid correction of hyponatremia. There were high signal intensities in the pons and bilateral deep gray nuclei on T2-weighted MRI images, and linear hyperintensities along the cerebral cortices on T1-weighted images with a diffuse gyriform enhancement. MR spectroscopic findings showed a decrease of the N-acetyl aspartate peak and an increase in those of the lipid and lactate complex. The case demonstrates that a severe form of osmotic demyelination syndrome accompanying cortical laminar necrosis can result from the rapid correction of hyponatremia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pons
/
Magnetic Resonance Imaging
/
Cerebral Cortex
/
Demyelinating Diseases
/
Aspartic Acid
/
Coma
/
Lactic Acid
/
Hyponatremia
/
Necrosis
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Journal of Clinical Neurology
Year:
2005
Type:
Article
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