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Isolated Myeloid Sarcoma Presenting as Cord Compression by Paraspinal Mass / 이화의대지
The Ewha Medical Journal ; : 17-22, 2016.
Article in English | WPRIM | ID: wpr-147091
ABSTRACT
Myeloid sarcoma is a rare tumor mass consisting of immature granulocytic cells occurring in an extramedullary site or in a bone. It has often been observed during the course of an acute leukemia, myelodysplastic syndrome or myeloproliferative neoplasms, and it can involve any site of the body. However, it rarely present in the absence of bone marrow infiltration, especially for the isolated spinal myeloid sarcoma. In this report, we describe a case of isolated myeloid sarcoma that showed spinal compression. A 66-year-old male, with no underlying disease or medication history, presented with a progressive back pain and numbness in bilateral lower extremities that had begun two weeks before. He was diagnosed with myeloid sarcoma with no evidence of bone marrow involvement. Tumor cells were positive for CD34, c-KIT, and Bcl-2 on the immunohistochemical stain. He was treated with systemic chemotherapy with daunorubicin plus cytosine arabinoside and achieved a partial response.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Spinal Cord Compression / Bone Marrow / Myelodysplastic Syndromes / Leukemia / Daunorubicin / Back Pain / Cytarabine / Sarcoma, Myeloid / Lower Extremity / Drug Therapy Limits: Aged / Humans / Male Language: English Journal: The Ewha Medical Journal Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Spinal Cord Compression / Bone Marrow / Myelodysplastic Syndromes / Leukemia / Daunorubicin / Back Pain / Cytarabine / Sarcoma, Myeloid / Lower Extremity / Drug Therapy Limits: Aged / Humans / Male Language: English Journal: The Ewha Medical Journal Year: 2016 Type: Article